Infantile Osteomyelitis Secondary to Malignant Osteopetrosis
نویسندگان
چکیده
منابع مشابه
A Case Report of Malignant Infantile Osteopetrosis
BACKGROUND Malignant infantile osteopetrosis (MIOP) presents early in life with extreme sclerosis of the skeleton and reduction of bone marrow spaces. Since there is a defect in the bone marrow, the disease can cause anemia, extramedullary hematopoiesis secondary to anemia leading to hepatosplenomegaly, cranial nerves compression and severe growth failure. This disorder is often lethal within t...
متن کاملMalignant infantile osteopetrosis presenting with neonatal hypocalcaemia.
Presentation characteristics were reviewed in 14 children from 12 families with malignant infantile osteopetrosis seen at two large referral centres for bone marrow transplantation. Children from six of these families presented initially with symptoms of hypocalcaemia. These comprised early or late neonatal convulsions in six cases (corrected serum calcium < 1.5 mmol/l), and vomiting and irrita...
متن کاملMalignant infantile osteopetrosis: otolaryngological complications and management.
OBJECTIVES To inform otolaryngologists about upper airway obstruction requiring tracheotomy and other otolaryngological manifestations of malignant infantile osteopetrosis (MIOP) and to discuss pathophysiological features, management, and new treatment strategies in MIOP. DESIGN Ongoing case series combined with a retrospective chart review. SETTING International tertiary pediatric hospital...
متن کاملMaxillary Osteomyelitis Secondary To Osteopetrosis – A Rare Case Report
Osteomyelitis of the mandible at a young age may occur as a complication of immunocompromised status or bone disorders. Osteomyelitis rarely occurs in the maxilla due to thin bone and collateral blood supply of the maxillary bone. We report here, a rare case of maxillary osteomyelitis that led to the diagnosis of the underlying condition of osteopetrosis. The clinical and radiographical feature...
متن کاملA Novel Mutation in SNX10 Gene Causes Malignant Infantile Osteopetrosis
BACKGROUND Osteopetrosis is a group of genetically heterogonous diseases and the main feature of that is increased bone density due to osteoclast's abnormality. It has three clinical forms based on inheritance pattern, severity and age of onset: the dominant benign form (ADO), the intermediate form (IRO) and the recessive severe form (ARO). One of the recently discovered genes for ARO form is S...
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ژورنال
عنوان ژورنال: Journal of Maxillofacial and Oral Surgery
سال: 2011
ISSN: 0972-8279,0974-942X
DOI: 10.1007/s12663-010-0115-7